Having loaded on a Hornady LNL AP for five years I recently switched to the Dillon 650. It is by far the least finicky if you want to load large volumes of any caliber in a short period of time. It does however have a much higher cost to get fully setup in each caliber, especially if you do quick change kits for each caliber (highly recommend doing so), also I'd suggest a separate toolhead for resizing of rifle brass. As you can see, it can get expensive so you have to define what kind of expectations you have and how much you really want to load.
The Hornady LNL AP is a great press which in many ways is easier to setup and change calibers, however it does not have nearly as reliable of a case feeder setup if you add one and it requires a bit of adjustment unlike the Dillon case feeder setup. Round output also is lower with the Hornady, but it is still easy to knock out several hundred rounds in an hour if you're really going at it.
Both are great presses, but both have some negatives such as price and speed of conversion in Dillon's case and with the Hornady a slower output and a finicky case feed setup.