Accuracy vs velocity

I am sure you can, especially if the bullet loses stability. It comes down to matching barrel to bullet to velocity.

Of course. But each rifle is different. I have 3 or 4 of 10 ish bolt actions that like it hot. The rest like a few steps down. It’s all about testing.

According to the fellas at Hornady, dispersion in your group size has a tendency to increase with charge weights (larger charge weight = more pressure = more Velocity)