Basically . . .NO! As you increase powder charge and speed, you're changing the "barrel time" for your bullet where it will be exiting the barrel at a different point within your barrel's harmonics.
Depending on where you are in the node, there may be a little room to do so . . . but there's not a lot of room to gain much velocity. If you feel you need more velocity, you need to find a different node with the higher velocity.