The larger screws and lug will help, but is not need in most applications, like hunting. The lug does help if you plain to shoot allot and the larger screws help if you plain on having a lot of weight attached to the base.
The biggest mistakes people make is not cleaning the oil or old Loctite out of the screw threads in the receiver and/or torque them correctly, so they back out. I have this happen to me on factory rifles and when I rushed to get every thing mounted. I have also seen that the screws are a tad long and bottom out on the barrel threads. You should always measure the screw length and make sure they will not bottom out before they are tight.
my self, I do run several 20 MOA lug base's made by MDT, but with the 6-48 screws with blue Loctite with out issues. As long as I do it right, I don't have issues. I also run there rings as well, for the price, you can not beat them for the quality.