I run a straight 280AI with 180gr Berger VLDs - F-open gun with a 32" Bartlein barrel. H4350 is the most accurate powder for my rifle. It's averaging about 2815fps and is capable of higher velocities with different powders, but again, H4350 trumps the others I have tried for accuracy. I'd try H4350 initially, I'm running 52.10gr and it's not a hot load, but smack bang in the middle of a node - try 51.5 - 53.5gr of H4350 and see how you go. If you want a slower powder, H4831sc but I reckon RL23 would be a bettr option - I'm going to give this powder a try shortly.