Most high performance bullets and cartridges have similar trajectory and wind drift out to around 800 yards. People will argue the difference, and chase it, but in reality your just splitting hairs. So you go with the cartridge with the least amount of recoil that has a pedigree of accuracy, that is why the 6 and 6.5 cartridges are the most popular in the PRS game. No one cares how much energy your bullet has, as long as it hits steel.
My first Snipers Hide Cup, I shot a 300WM. I excelled in the stages where targets we're at a distance, and usually prone, but it was a handicap on the barricade or positional stages. I ended up finishing at 72 out of 150 from what I recall? I did have a problem where the ejected cases were hitting my scope mount and randomly bouncing back into the action, so that and the short time limits didn't help me either.