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Developing load (nodes) and suppressors?

arrowem

Private
Full Member
Minuteman
Jun 7, 2017
12
1
Hi, I am going to be developing 2 caliber loads (223 6.5CM) and will be doing the ladder test for finding nodes. My question is would it change the preferable node zone by adding or changing suppressors. I pretty much suppress everything (13 stamps and counting) but if I develop a load to "perfection" I don't want to ruin it by either -not using a suppressor or using a different suppressor (not including POI shift obviously)