Re: rifle upper on carbine lower
It'll be fine...but depending on which buffer weight/spring you are running, going from the .308 to the .243 may cause issues but not likely.
I have a couple different uppers that I switch out on an Armalite pattern AR-10 lower that has a UBR (carbine buffer setup) installed. One upper is a shorty 16" AR-10 length carbine gas setup while the others are 20" and 24" rifle-length gas systems and they all function flawlessly on the same lower.