Re: S&W 460?
For an able-bodied man familiar with handling and shooting firearms, it's a lot of recoil, but entirely manageable. The 8" model is comped, has plenty if mass, and particularly, plenty of mass up front to help with muzzle climb.
My best advice is to NOT let it psyche you out. All you need is a firm grip (NOT a Kung Fu death grip), and to let it do its thing. Easier said than done, of course.
When I'm not being a bitch, I can shoot my 500 beautifully. Occasionally though, I let it psyche me out, my vag starts bleeding, and I wing shots all over the place...