is there a reason that you are stuck on a 5R
i have never seen a difference in life or accuracy with a 5R compared to a regular 4 groove (keieger, Bartlein, schnieder, broughton, stainless and hammer forged).
did a 388 LM in a 3 groove, there used to be some that believed that the throat of a 3 groove would not erode as fast because of the larger rifling.
i didnt find that to be the case either.
the percentage of land to groove should be the same amount of total material regardless of the number of grooves.