30-06 .308 .270 I like practical things.
But, when my Uncles and Dad passed, and their guns came to me. I made it a point to shoot at least 1 white tail with each gun. So, .300 Savage, .32 Win Special, .303 Savage and 30-30. With a nice soft point bullet that opens up, they all work. Loaded the .300 Savage with a 165 grain Sierra Pro Hunter , old lot with a big open hollow point. Wow I have never seen any thing bleed like that.
With the .270 using a Hornady Interlock I shot a deer broad side at short range, but no blood loss. Thought I had missed and was pretty upset. Finally found some drops of blood and recovered the animal. Shot through both lungs, and it looked like I they had a pencil poked through them, zero expansion. The next year I used a Sierra Pro Hunter and it blew the heart apart, and had a big exit hole. Dumped him.
The point is, with a good bullet, of reasonable size, they all work for white tail.