Before firing any factory rifle, it should be bedded and diamond lapped. This rifle has a blued barrel, and the odds are that some bluing is in the muzzle, which needs to be removed (by lapping). The stock bedder will be able to check for proper action screw length, and will grind those if they are too long. A barrel this heavy needs a "saddle" of bedding material under the first few inches of barrel forward of the recoil lug. Go to Georgia Precision website for proper cleaning technique. However, if you shoot moly-coated bullets, the cleaning process is easier. The barrel needs lapping every 300-500 rounds, and you could use Tubb Fire-lapping bullets for that purpose. This applies even after the rifle is sent to the factory for evaluation. I recommend getting in touch with Garland Gilbreath, who does bedding. If you want lapping done, check with your local high-power rifle shooters, and find one who does diamond lapping. Edited for new information: I am not familiar with Cerakote, but you need to look in the muzzle and shine a light onto a sliver of paper in the muzzle. If you do not see a proper mirror finish, you most likely need lapping. The grooves may look dark and streaky, which is either from the coating, or due to improper cleaning. You may also see copper-colored fouling on the lands. The copper color would indicate fouling; and with proper lapping, the fouling should not occur until after quite a few rounds, and should clean up fairly quickly. 5R rifling is supposed to help fouling.
Edited for further new information: I also recommend checking a fired case to see if a bullet will drop through it. If not, it means you might have a custom chamber, which could be in keeping with the info from the previous poster about the semi-custom nature of this model. If a bullet does not drop through the fired case, do not shoot the rifle until a standard finish reamer has been run through it, including the neck. Diamond lapping obviates the need for any barrel break-in. Many of the custom barrel makers diamond lap their barrels, but a Remington barrel that is lapped can shoot about 0.5 MOA for 5 shots most of the time. It takes me about 1 hour to diamond lap a barrel, and the usual break-in (which is not as good anyway) takes several hours. I may have to edit again after further posts are made in response to your issue. There has already been a lot of good information, but you need something definitive upon which to take your next action. The last time one of my buddies shot groups like yours, he had too tight a chamber neck, which is a dangerous situation. I am passing on to you what he told me.