I have a 22" 1-8 twist that shoots lights out. NO problems AT ALL with 300 SMKS or boogers.
Good luck, Id jump on it if good deal.
Also, similar to 308, you don't lose a lot with a short barrel 338. 92gr of H100 moving 300's 2720 is supersonic way past a mile. I laugh out loud every time I see/hear about a long barreled 338. No one likes a 30lb rifle.
Obviously if you only have BR plans then yes optimize it. But this isn't a BR site. Think practical.
Luck,
DT