Few things: what are you shooting, what are your goals. Which bullet, powder, case.
10 loads x.3 is fine, but you will probably find two accuracy nodes in your spread about a grain apart. If you will be shooting close distance, there is no need to hit the highest node, as you will just reduce case life.
For instance, many guys shoot 308, and a 178 amax over some varget. There are two poplular nodes around 44.4 and 43.5. At 44.4 you will get decent groups, a bit more velocity and downrange energy. The trade-off is case life. If shooting 500, then focus toward the lower node. There is no need to run the whole gambit of loads if you will choose the lower anyway.
So back to your original question.. I use a common sighting target and shoot 5 rounds of each in a round robin, this is because sometimes I pull a shot and its easier to x that one out and still get a good group from 4 shots, than 2. If you plan to shoot all 10 loads, do five and then give your rifle a rest (cool down).
Also if you cleaned your rifle beforehand, have enough rounds to foul the barrel first.