I've never had an issue with this. I remember thread(s) popping up in the past where guys were saying they needed more than the specified 49 in-lbs.
My technique when installing the barrel is to point the gun straight up, with the buttstock on the ground. Holding the gun tight between my legs to resist it twisting, I tighten the barrel as hard as I can with both hands. If you have an AX and the barrel is short, it's probably best to remove the handguard.
Then with the rifle on a bench (or at least on the ground with a bipod) I torque the Quick-Loc screw to 49 in-lbs. I run a TBAC Ultra suppressor with the CB brake, and after a 100+ round day, it's carbon'd on there pretty damn tight. I've never had the barrel move whatsoever when unscrewing the suppressor.
One other thing to consider, is the Quick-Loc screw is 49 in-lb for a reason. That screw size can only be torqued so far before it stretches and plastically deforms. I ran the numbers back when those original threads were popping up, and I think the guys going to even the 60-70 in-lb range could be stretching that bolt. So going to 70 or 80 in-lb might give you the false sense that "more torque = better", when in reality once you reach a certain threshold you're stretching the bolt past the point where it will elastically return, and then it will need more and more torque to reach the desired result. That all depends on the grade of the screw, so maybe AI specs something that can take 100 in-lb, but I can't say for sure.