Easy, and it's my wife's, my friend's, his daughter's and a few other folks favorite too. The 6" 686+. It's a no lock, a -5 I think? Super smooth, super light trigger, I hit 5 of 7 shots at 300m standing on an army steel silhouette. Best I've ever done with any handgun.
But I actually carry a 340PD when I carry a revolver. Nothing like being able to tell the bad guy "This is gonna hurt me more than you..." Well, not really but you get the idea. I've had keys weigh more than this thing.
My wife is the big wheel gunner, she carries a 649 no lock.
I hate the .22 317 snub the most. Stiff as shit and inaccurate as hell, but my wife likes it for walking the dog. Lighter even than the 340PD.