Some of the differences between powder varieties involve coatings and shapes.
Coatings are intended to provide ignition retardation, which is another way of saying they control burning rates.
They also tend to survive combustion and end up serving as a dry bore lube, in many ways similar, and some ways dissimilar, to moly. We call their accumulation carbon fouling, but that's really understating both the complexity and the importance coatings apply to the science of bore drag.
Granule shapes are purposed to add another factor to burn rate, via the granule weight/surface area ratio. The greater area per unit weight, the faster it ignites.
This shape attribute also affects the way powder settles, and affects load density, weight per unit volume, and individual load burn consistency. The more dispersed the powder is within the case, the faster ignition proceeds; so cases with empty space can tend to have less consistent ignition curves and muzzle velocities; due to differences in the way the charge settles within the casing just prior to ignition.
This is a reason why minimum charges exist, to reduce pressure spikes caused by excessively rarified granule distribution. The primer ignition process shocks a loosely packed charge, dispersing it into suspension within the case. Heat propagation is via infrared radiation, and too few granules per unit volume in a suspension means that the infrared energy can irradiate more granules at a time, accelerating ignition to an unsafe degree.
A ball powder, like H414, is different in several ways from a stick powder, like H-4350.
In addition to shape differences, H-414/W760 also has a quite different coating technology from H-4350. The load density characteristics of H-414 tends to leave more empty space per unit weight. Its older technologies count heavily on graphite's electrically conductive properties, primarily purposed to prevent static charge buildup, and a resulting high probability for unintentional static spark-induced ignition during transport
H-414 uses a heavier coating to offset the natural tendency of smaller, closer packed ball granules to ignite faster, leaving a heavier degree of 'carbon' fouling. That coating is of an older technology, being largely graphite. Newer technologies, like H-4350's 'Extreme' coating, incorporate different/more complex chemistries, altering fouling rates and bore friction values, along with temperature sensitivity characteristics.
The 'Extreme' coatings are intended to minimize velocity variances due to temperature changes, and may work by moderating burn rate, bore friction, or both.
Greg