I can geek out on handgun reloading all day long... LOL. RampedRaptor has some good stuff above.
Relative to rifle, handgun runs much faster powders obviously. And, with some cartridges like .45 ACP and .38 Special, the classic "preferred" loads for accuracy involve a small charge of a very fast burn rate powder. This can be tricky (read: potentially dangerous) for a couple of reasons - first, you can frequently charge a case 2-3 times (or more in .38 Special w/ Bullseye) before you notice it visibly. Second, because the pressure curve rises so quickly with powder that fast, the load isn't going to be very tolerant of things like setback - that can be an issue in a pistol, if you don't have adequate bullet tension. A progressive press tends to fix the first problem - especially one that has auto-indexing like the 650. You basically have to purposefully try to double charge a case.
Sorting cases... for a revolver, not super critical, but for a pistol might be important depending on the cartridge and the cases you have. For .45, it's not as much of an issue, but there's enough difference in the various brands of 9x19 brass that you could potentially have extraction issues with one brand, and zero issues with another (depending on your pistol). As RR alludes to above, be aware that there are .45 cases running around out there that use small pistol primers. The brass is mostly originally loaded as lead-free, if I recall correctly.
Most popular .45 loads run a faster powder... Bullseye, Titegroup, VV N310 or N320 (I love N320, personally), Win 231, etc. 231 and Bullseye were the classic .45 powders for a long time. WST... is popular with some folks including on this thread. For .45, it seems to be pretty ok. It's not super tolerant of setback, though - the only case head separations I've seen in handgun involve WST, but that was in .40. If you're looking for max velocity or +P range, you need to go to a slower powder, obviously. N340, Unique, and others. I haven't tried Longshot in
Other than the risk of a double charge, loading for .45 is about as easy as it gets - it's generally super tolerant of user error, and will generally shoot ok even with sub-optimal loads. Heck, as long as you're talking normal pressure loads, you can literally load up cracked cases and shoot them, as long as they'll hold a bullet - not that I would recommend that at all, but... point is, it's a super low pressure cartridge, and is very forgiving.
Even though you are using carbide dies (you should be, if you're not), you want to lube your cases with something like Hornady One Shot, or Dillon Case Lube (it's a lanolin based lube) - neither will affect your primers. Contrary to fairly popular belief, it is safe to tumble your loaded ammo for a short period of time to remove the lube after you've loaded them (but be careful if you are loading hollow points - the media can stick in there and cause jams in your pistol later).
Final thought - the powder charge actually makes up a reasonable amount of the recoil energy. Enough that you can feel a significant difference between powders (heavier charge weight = higher energy, and hence heavier recoil). It doesn't seem like a couple grains should make that much difference, but when you calculate the energy difference between them, doubling the charge weight becomes noticeable. So, for lower recoil, you also want to trend toward faster powders. The trade off being that faster powders don't fill the case as much, and are easier to double/triple charge (which you mitigate with your press).
