IMO there's only one way it can go bad on you, and that's necking down: necking down from 6.5 stuff is a more complicated process in that to do it without any unwanted surprises you'll need to do it in 2 separate steps with 2 separate progressively smaller/tighter bushings... and if you lube them adequately and everything goes right, then if they don't fit... fuck, now you're going to have to become a neck turner lol.
Necking up from .22 stuff is a simple, no lube necessary, 1-step process using a TiNi/BkNi/carbide mandrel die (I use a TiNi Sinclair .241 Neck Turning Arbor). It's as fool-proof as it gets (a term you hear used incorrectly too much, but I'm a fool and even I can do it without fucking it up lol). The brass will conform to your neck/chamber on the first firing.