If its ammo you dont normally use, fire off a good 10 rounds before mounting the can to make sure they are all shooting straight and not tumbling or anything.
Know that the can will get hot if you shoot somewhat quickly. if you are going 1 or 2 rounds a minute it wont be bad. But start doing even 5 rounds a minute and itll get pretty hot to the touch. With that in mind bring something to set it on when you move to the garand to let it cool (i use a microfiber towel).
Know you might get "gas to the face". Just a by-product of semi-auto surpressed.
Shooting suppressed your brass, BCG, and gun will get more dirty. If you pick up your brass id bring some sort of hand cleaner and paper towels if you dont normally.
Still wear double hearing....556 is still decently loud with the crack from supersonic. Even subsonic stuff i wear least earplugs for plinking.
And mostly....have fun! Enjoy your new toy! And report back how you like it and how the accuracy is with it!