Re: barrel twist
1:12 will accurately shoot 155-175gr projectiles. That is from experience.
1:12 is preferred for 168gr. according to the helpful folks at Pac-nor (where I will be buying my next blank).
Decide WHAT weight bullet will do what you want, then call your barrel manufacturer and ask them what rifling style and twist rate to use for that projectile.
Or just call a custom riflesmith and tell him what you want to shoot and have him spec it out for you.